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OT: Coronavirus Resources - and other things to not worry about

For the folks at home not knowing which variants to panic about:
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The vaccines all likely do a fine job reducing severity except MAYBE the oxford/AZ one with the SA variant. Brazilian one seems like it'll be fine.
 
I’m 70 something and I don’t really expect a chance to getting vaccinated before at least the end of April but more likely sometime in May I hope. My understanding is that Ottawa has given out a total of just over 51,000 shots (first and second)
I’ll gladly take whatever vaccine is offered.

💉 I prefer one against the COVID-19 though. 😇
 
I’m 70 something and I don’t really expect a chance to getting vaccinated before at least the end of April but more likely sometime in May I hope. My understanding is that Ottawa has given out a total of just over 51,000 shots (first and second)
I’ll gladly take whatever vaccine is offered.

💉 I prefer one against the COVID-19 though. 😇
Doesn't help that they're not giving the Oxford vaccine to anyone over 65. So the wait won't get any shorter for them after that approval unfortunately.
 
For the folks at home not knowing which variants to panic about:
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The vaccines all likely do a fine job reducing severity except MAYBE the oxford/AZ one with the SA variant. Brazilian one seems like it'll be fine.
is there any actual evidence regarding vaccine efficacy respecting the P1 variant, beyond the J&J trial?

and do we have any hard evidence whatsoever regarding Pfizer & Moderna efficacy on the various variants? I thought we did but this chart is silent on it...
 
Doesn't help that they're not giving the Oxford vaccine to anyone over 65. So the wait won't get any shorter for them after that approval unfortunately.
yeah NS is giving them to the like 50-65 demographic on a first come first served basis. and I assume we're not even done with the over 80s yet either... fun fun.
 
is there any actual evidence regarding vaccine efficacy respecting the P1 variant, beyond the J&J trial?

and do we have any hard evidence whatsoever regarding Pfizer & Moderna efficacy on the various variants? I thought we did but this chart is silent on it...
1. We have this:



This is pretty sound evidence that its immunity escape is not as strong as the SA variant. The Brazilian variant may be more transmissive (currently unknown) but it does not have a significant ability to evade immunity (at least compared to the SA variant). The only real concern for immunity escape is the SA variant and even that seems relatively manageable for most of our vaccines. We'll eventually get boosters to combat that one though I think.

2. We have real world data on Pfizer doing a great job in the UK and Israel. The UK variant is pretty much 100% predominant in both of those places. It seems like Oxford is doing pretty much just as well as Pfizer in the UK at least for the first dose (maybe even better). I don't think anyone there has received 2 doses as they're getting as many people done as possible; it's probably likely that the second dose is what would put the Pfizer vaccine ahead in the end but who knows? Real world data is a lot different than the trials as the trials. Hard to compare when the trials were all done in completely different environments with different levels of transmission and different mutations. Pfizer may not look as great compared to the others on a level playing field.

We do not know how Pfizer/Moderna will do with the SA variant but we can assume a pretty decent decrease in effectiveness as we saw with Novavax and J&J. However it's not going to be an all or nothing thing. We'll have protection and we may even have great protection from severe cases. It's a pretty fair assumption to make. Probably will still need to be cautious around seniors though until we get our boosters.
 
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1. We have this:



This is pretty sound evidence that its immunity escape is not as strong as the SA variant. The Brazilian variant may be more transmissive (currently unknown) but it does not have a significant ability to evade immunity (at least compared to the SA variant). The only real concern for immunity escape is the SA variant and even that seems relatively manageable for most of our vaccines. We'll eventually get boosters to combat that one though I think.

2. We have real world data on Pfizer doing a great job in the UK and Israel. The UK variant is pretty much 100% predominant in both of those places. It seems like Oxford is doing pretty much just as well as Pfizer in the UK at least for the first dose (maybe even better). I don't think anyone there has received 2 doses as they're getting as many people done as possible; it's probably likely that the second dose is what would put the Pfizer vaccine ahead in the end but who knows? Real world data is a lot different than the trials as the trials. Hard to compare when the trials were all done in completely different environments with different levels of transmission and different mutations. Pfizer may not look as great compared to the others on a level playing field.

We do not know how Pfizer/Moderna will do with the SA variant but we can assume a pretty decent decrease in effectiveness as we saw with Novavax and J&J. However it's not going to be an all or nothing thing. We'll have protection and we may even have great protection from severe cases. It's a pretty fair assumption to make. Probably will still need to be cautious around seniors though until we get our boosters.

thanks for all this
 
Looks like those oxford vaccines we just received will be going to 60-64 year olds. I don't know if I should tell my mom to get it or not. A little concerned at the lack of efficacy on the SA variant but there's no denying it works great on the others. For that reason, I'm out. She can decide for herself.
 
If we're doing the everyone gets one dose and delay the second dose thing we may be all due in June tbh. We'll probably have the supply for it at the very least. Second shots probably August-September.
 
so as an under-50 person who doesn't work in a high-risk environment, when am I realistically getting a vaccine?

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Looks like those oxford vaccines we just received will be going to 60-64 year olds. I don't know if I should tell my mom to get it or not. A little concerned at the lack of efficacy on the SA variant but there's no denying it works great on the others. For that reason, I'm out. She can decide for herself.

I’m surprised they are not offering them to some of the essential workers who face the public every day (like grocery store workers).
In any case this batch expires in a month so I guess they decision has to be made quickly. If I was in the 60-65 age group and had the option I’d probably go for it. People are unlikely to get a choice of which vaccine they get at anytime so that could be what they’d get later anyway.
 
I’m surprised they are not offering them to some of the essential workers who face the public every day (like grocery store workers).
In any case this batch expires in a month so I guess they decision has to be made quickly. If I was in the 60-65 age group and had the option I’d probably go for it. People are unlikely to get a choice of which vaccine they get at anytime so that could be what they’d get later anyway.

Yeah, I think it's very hard to separate by profession. Does a Sobeys worker who only stock shelves get it, or only the cashiers? What counts towards "essential"? You could answer that, but I think it gets murky fast, so easier to go by broad age groups as the basis.

But yeah, I think you just take whatever shot is available when the time comes. Even if you get one that's useless against a variant, from what I understand, there shouldn't really be any adverse reactions to mixing and matching later, so I assume there will be an "Oxford SA Booster" that you'd need to get next year if that variant gets more prevalent.
 
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